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Research

For Men: Bio-Identical Hormone Replacement Therapy Research Articles

'Testosterone for Men' is just the beginning!

LIFEFORCE Medical Institute goes far beyond providing 'Testosterone for Men' and 'Bio-Identical Hormone Replacement Therapy" (BHRT) for women. We also offer a variety of healthy aging supplements, prescriptions, anti-aging age management programs, tests and fitness protocols that help radically improve health and 'defy age.' Dr. Mark Rosenbloom founded and based LIFEFORCE in the Chicago area after years of research on healthy aging, which included studies of other companies in the field such as Bodylogic and Cenegenics. Once he was certain he could dramatically improve upon the services offered by these other companies, he launched the LIFEFORCE Medical Institute.

Research and Articles on the Risks and Benefits of Testosterone Replacement
There have been thousands of studies on the use of Testosterone Replacement Therapy (TRT) for men. Benefits of such replacement therapy have been clearly demonstrated. However, many misconceptions about the potential risks of such therapy persist. We have selected some of the best articles about testosterone for you to review (and can furnish more to you on request). Just click on the topic below for a link to these studies in the U.S. National Library of Medicine or to other reliable sources of information.

1. Summary:

a. A practical guide to male hypogonadism in the primary care setting. Int J Clin Pract.; Dandona P, Rosenberg MT.; Division of Endocrinology, Diabetes and Metabolism, State University of New York at Buffalo and Kaleida Health, Buffalo, NY, USA.

2.  Review Finds No Evidence of Testosterone Harm. Testosterone defenders found 'no convincing evidence' of heart risks.   Read the article

3. Testosterone levels decrease as we age:

a. A population-level decline in serum testosterone levels in American men.  J Clin Endocrinol Metab.; Travison TG, Araujo AB, O'Donnell AB, Kupelian V, McKinlay JB.; New England Research Institutes, 9 Galen Street, Watertown, Massachusetts 02472, USA.

b. Age-related changes in serum testosterone and sex hormone binding globulin in Australian men: longitudinal analyses of two geographically separate regional cohorts.  J Clin Endocrinol Metab.;  Liu PY, Beilin J, Meier C, Nguyen TV, Center JR, Leedman PJ, Seibel MJ, Eisman JA, Handelsman DJ.;  Department of Andrology, Concord Hospital and ANZAC Research Institute, University of Sydney, Sydney, New South Wales 2139, Australia.

4. Low testosterone levels increase risk of death:

a .Low serum testosterone and mortality in older men.  J Clin Endocrinol Metab. ;  Laughlin GA, Barrett-Connor E, Bergstrom J.;  Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0631C, La Jolla, California 92093, USA.

5. Low testosterone levels increase risk of heart disease:

a. Welcoming low testosterone as a cardiovascular risk factor. Maggio M, Basaria S. Int J Impot Res. ;  Department of Internal Medicine, Division of Endocrinology & Metabolism, University of Parma, Parma, Italy.

6. Testosterone therapy improves libido / sexual response:

a. Subjective sexual response to Testosterone Replacement Therapy based on initial serum levels of total testosterone.  J Sex Med.;  Reyes-Vallejo L, Lazarou S, Morgentaler A.;  Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

7. Testosterone treats depression:

a. A randomized, double-blind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression).  J Clin Psychiatry.; Shores MM, Kivlahan DR, Sadak TI, Li EJ, Matsumoto AM.;  Geriatric Research, Education, and Clinical Center, Veterans Affairs (VA) Puget Sound Health Care System, Seattle, Wash. 98108, USA.

8. Testosterone does NOT cause prostate cancer:

a. Testosterone Replacement Therapy and Prostate Risks: Where’s the Beef?   Abstract only: Can J Urol.; Morgentaler A.; Division of Urology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

For Women: Bio-Identical Hormone Replacement Therapy Research Articles

Research and Articles on Risks and Benefits of Bio-Identical Hormone Replacement Therapy
There are tens of thousands of studies that describe the risks and benefits of hormone replacement therapy for women. Most of the studies in the past have been financed by drug companies and have shown that conventional hormone-replacement therapy has significant risks and that women should be careful when considering hormone replacement therapy. These studies have been done with patented synthetic hormones – substances which do have significant potential toxicity. Dr. Rosenbloom ONLY prescribes Bio-Identical Hormone Replacement Therapy (BHRT). BHRT has been shown to be MORE EFFECTIVE and MUCH SAFER than synthetic hormones. We have selected some of the best articles for you to review (and can furnish more to you on request). Just click on the topic below for a link to these studies in the U.S. National Library of Medicine or to other reliable sources of information.

1. Summary of Risks & Benefits

a. 12 reasons to be happy about hormone replacement therapy: a guide for patients.  

2. Bio-Identical Hormones are Safer and More Effective:

a. The Bio-Identical hormone debate: are Bio-Identical hormones (estradiol, estriol, and progesterone) safer or more efficacious than commonly used synthetic versions in hormone replacement therapy?
Postgrad Med.;   Holtorf K.;  Holtorf Medical Group, Inc., Torrance, CA 90505, USA.

b. Could transdermal estradiol + progesterone be a safer postmenopausal HRT? A review.
Maturitas. ; L'hermite M, Simoncini T, Fuller S, Genazzani AR.; Department of Gynecology and Obstetrics, Université Libre de Bruxelles, Bruxelles, Belgium.

c. Premature menopause or early menopause: long-term health consequences.
Maturitas.;  Shuster LT, Rhodes DJ, Gostout BS, Grossardt BR, Rocca WA.; Womens Health Clinic, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

3. Hormone Replacement Therapy Can Improve Osteoporosis:

a. Effects of continuous combined hormone replacement therapy and clodronate on bone mineral density in osteoporotic postmenopausal women-A 5-year follow-up.
Maturitas. ; Tuppurainen M, Härmä K, Komulainen M, Kiviniemi V, Kröger H, Honkanen R, Alhava E, Jurvelin J, Saarikoski S.; Department of Obstetrics and Gynecology, Kuopio University Hospital, Kuopio, Finland; Bone and Cartilage Research Unit, Clinical Research Center, University of Eastern Finland, Kuopio, Finland.

4. Hormone Replacement Therapy Helps Prevent Heart Disease:

a. Hormone therapy and risk of myocardial infarction: a national register study.
Eur Heart J. ; Løkkegaard E, Andreasen AH, Jacobsen RK, Nielsen LH, Agger C, Lidegaard Ø.; Gynaecological Clinic, Rigshospitalet, Copenhagen Ø, Denmark.; Comment in: Womens Health (Lond Engl).

5. Bio-Identical Hormone Replacement Therapy Does Not Increase Breast Cancer:

a. Combined hormone replacement therapy and risk of breast cancer in a French cohort study of 3175 women. Climacteric. ; de Lignières B, de Vathaire F, Fournier S, Urbinelli R, Allaert F, Le MG, Kuttenn F.; Service d'Endocrinologie et Médecine de la Reproduction, Hôpital Necker, Paris, France.

6. Hormone Replacement Therapy Promotes Healthy Skin and Looking/Feeling Younger:

a. Oestrogen and age estimations of perimenopausal women. Lancet. ; Wildt L, Sir-Petermann T.

b. Treatment of skin aging with topical estrogens.
Int J Dermatol. ; Schmidt JB, Binder M, Demschik G, Bieglmayer C, Reiner A.; Department of Dermatology, University of Vienna Medical School, Austria.

c. Effects and side-effects of 2% progesterone cream on the skin of peri- and postmenopausal women: results from a double-blind, vehicle-controlled, randomized study.
Br J Dermatol. ; Holzer G, Riegler E, Hönigsmann H, Farokhnia S, Schmidt JB.; Division of Special and Environmental Dermatology, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria. Erratum in: Br J Dermatol. 2005 Nov;153(5):1092. Schmidt, B [corrected to Schmidt, JB].

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